In this video, Dr. Andrew Kuykendall provides an overview of how
myeloproliferative neoplasms (
MPNs) are
diagnosed. He explains that the process often begins with a routine blood test that shows unusually
high levels of
red blood cells,
white blood cells, or
platelets. If an MPN is suspected, further testing is done to look for common
genetic mutations such as
JAK2,
CALR, or
MPL, which help confirm the diagnosis. A
bone marrow biopsy is also recommended to better understand the disease and identify its specific type, especially if the diagnosis remains uncertain after blood and genetic tests.
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