In this video, Dr. Gabriela Hobbs explains how
essential thrombocythemia (
ET) is
managed and
treated. Management begins with assessing the patient's
risk of blood clots to determine if
aspirin or
medications to lower platelet counts (
cytoreductive therapy) are needed. High-risk patients may receive
hydroxyurea,
interferons (like Pegasys or ropeginterferon), or occasionally
ruxolitinib or
anagrelide. Dr. Hobbs also discusses the importance of patients
staying in communicaton with their care team, and how
treatment decisions take into account a patient's risk for bleeding and disease-related symptoms. She provides an overview of special considerations for younger patients, particularly women planning
pregnancy. Finally, Dr. Hobbs highlights
emerging therapies under study that aim to better control blood counts and reduce mutation levels in ET.
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