Hematologist-oncologist, Dr. Anand Patel, explains
why and how myelofibrosis (
MF)
develops. He describes MF as a chronic blood cancer caused by
acquired gene mutations that arise over time in bone marrow stem cells, rather than being inherited. As these mutated cells multiply, they release substances that cause
scarring (
fibrosis)
of the bone marrow, which interferes with normal blood cell production. Dr. Patel also explains that MF is most commonly diagnosed in people over age 60, though it can occur at younger ages too.
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