How is myelofibrosis (MF) diagnosed? — Expert Video

In this video, Dr. Anand Patel explains how myelofibrosis (MF) is diagnosed. MF is often first suspected when blood tests show abnormal blood counts or when symptoms such as anemia, abdominal bloating, or an enlarged spleen raise concern. Dr. Patel emphasizes that a bone marrow biopsy is required to confirm the diagnosis, as it shows scarring in the bone marrow and allows for genetic and chromosome testing. He also discusses how changes in blood counts or spleen size can signal progression from polycythemia vera or essential thrombocythemia to MF. He also describes how blood and bone marrow testing are used to identify mutations that help guide risk assessment and treatment decisions.

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