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  3. What is myelofibrosis (MF)? — Expert Video
Understanding and Diagnosing Myelofibrosis (MF) — Animation
Understanding and Diagnosing Myelofibrosis (MF) — Animation
Managing and Treating Myelofibrosis (MF) — Animation
Managing and Treating Myelofibrosis (MF) — Animation
Understanding and Diagnosing Myelofibrosis (MF) — Slide Show
Understanding and Diagnosing Myelofibrosis (MF) — Slide Show
Managing and Treating Myelofibrosis (MF) — Slide Show
Managing and Treating Myelofibrosis (MF) — Slide Show
Expert Videos
What is myelofibrosis (MF)?
1. What is myelofibrosis (MF)?
Why and how did my myelofibrosis (MF) arise?
2. Why and how did my myelofibrosis (MF) arise?
How is myelofibrosis (MF) diagnosed?
3. How is myelofibrosis (MF) diagnosed?
What are the signs, symptoms, and expectations of living with MF?
4. What are the signs, symptoms, and expectations of living with MF?
How is myelofibrosis (MF) managed and treated?
5. How is myelofibrosis (MF) managed and treated?
What new therapies are being developed for myelofibrosis (MF)?
6. What new therapies are being developed for myelofibrosis (MF)?
How can anemia be managed in myelofibrosis (MF)?
7. How can anemia be managed in myelofibrosis (MF)?
Patient Videos
Ned's story: How did you find out you had myelofibrosis (MF)?
8. Ned's story: How did you find out you had myelofibrosis (MF)?
Ned's story: What challenges and successes have you had with MF treatment?
9. Ned's story: What challenges and successes have you had with MF treatment?
Ned's story: What advice do you have for others on their journey with MF?
10. Ned's story: What advice do you have for others on their journey with MF?

What is myelofibrosis (MF)? — Expert Video

Dr. Anand Patel of the University of Chicago explains that myelofibrosis (MF) is a subtype in the family of chronic blood cancers called myeloproliferative neoplasms (MPNs)—caused by abnormal signaling in the bone marrow that disrupts normal blood cell production. He describes how MF differs from related conditions such as polycythemia vera and essential thrombocythemia due to increased bone marrow scarring. Dr. Patel discusses how this scarring can lead to low blood counts, spleen enlargement, and other complications, and explains that MF can range from a slow-moving disease to more aggressive forms. He also outlines the differences between primary myelofibrosis and secondary myelofibrosis, which can develop from polycythemia vera or essential thrombocythemia.

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Other Modules:

Understanding MPNs

Understanding MPNs

Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Polycythemia Vera (PV)

Polycythemia Vera (PV)

Understanding and Diagnosing Myelofibrosis (MF) — Animation
Understanding and Diagnosing Myelofibrosis (MF) — Animation
Managing and Treating Myelofibrosis (MF) — Animation
Managing and Treating Myelofibrosis (MF) — Animation
Understanding and Diagnosing Myelofibrosis (MF) — Slide Show
Understanding and Diagnosing Myelofibrosis (MF) — Slide Show
Managing and Treating Myelofibrosis (MF) — Slide Show
Managing and Treating Myelofibrosis (MF) — Slide Show
Expert Videos
What is myelofibrosis (MF)?
1. What is myelofibrosis (MF)?
Why and how did my myelofibrosis (MF) arise?
2. Why and how did my myelofibrosis (MF) arise?
How is myelofibrosis (MF) diagnosed?
3. How is myelofibrosis (MF) diagnosed?
What are the signs, symptoms, and expectations of living with MF?
4. What are the signs, symptoms, and expectations of living with MF?
How is myelofibrosis (MF) managed and treated?
5. How is myelofibrosis (MF) managed and treated?
What new therapies are being developed for myelofibrosis (MF)?
6. What new therapies are being developed for myelofibrosis (MF)?
How can anemia be managed in myelofibrosis (MF)?
7. How can anemia be managed in myelofibrosis (MF)?
Patient Videos
Ned's story: How did you find out you had myelofibrosis (MF)?
8. Ned's story: How did you find out you had myelofibrosis (MF)?
Ned's story: What challenges and successes have you had with MF treatment?
9. Ned's story: What challenges and successes have you had with MF treatment?
Ned's story: What advice do you have for others on their journey with MF?
10. Ned's story: What advice do you have for others on their journey with MF?

Other Modules:

Understanding MPNs

Understanding MPNs

Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Polycythemia Vera (PV)

Polycythemia Vera (PV)

 

This educational activity has been developed by MPN Research Foundation in collaboration with Mechanisms in Medicine Inc.

This activity is supported by independent educational grants from Disc Medicine, GSK, Incyte, Merck, PharmaEssentia, Sumitomo Pharma, and Takeda.

We are also deeply grateful to the individual donors whose generosity supports the MPN Research Foundation's mission and programs like this one.

Thank you to the funders of You And MPN. All content is developed independently by MPN Research Foundation and Mechanisms in Medicine Inc., in collaboration with an Expert Faculty group; funders are allowed no influence on the content of You And MPN: Animated Patient® Guide to Myeloproliferative Neoplasms.

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This website is part of the Animated Patient® series developed by Mechanisms in Medicine Inc., to provide highly visual formats of learning for patients to improve their understanding, make informed decisions, and partner with their healthcare professionals for optimal outcomes.