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  3. How is polycythemia vera (PV) diagnosed? — Expert Video
Understanding and Diagnosing Polycythemia Vera (PV) — Animation
Understanding and Diagnosing Polycythemia Vera (PV) — Animation
Managing and Treating Polycythemia Vera (PV) — Animation
Managing and Treating Polycythemia Vera (PV) — Animation
Understanding and Diagnosing Polycythemia Vera (PV) — Slide Show
Understanding and Diagnosing Polycythemia Vera (PV) — Slide Show
Managing and Treating Polycythemia Vera (PV) — Slide Show
Managing and Treating Polycythemia Vera (PV) — Slide Show
Expert Videos
What is polycythemia vera (PV)?
1. What is polycythemia vera (PV)?
Why and how did my polycythemia vera (PV) arise?
2. Why and how did my polycythemia vera (PV) arise?
How is polycythemia vera (PV) diagnosed?
3. How is polycythemia vera (PV) diagnosed?
What are the signs, symptoms, and expectations of living with PV?
4. What are the signs, symptoms, and expectations of living with PV?
What are the risks with polycythemia vera (PV)?
5. What are the risks with polycythemia vera (PV)?
How is polycythemia vera (PV) managed and treated?
6. How is polycythemia vera (PV) managed and treated?
Patient Videos
Dana's story: How did you find out you had polycythemia vera (PV)?
7. Dana's story: How did you find out you had polycythemia vera (PV)?
Dana's story: What challenges and successes have you had with PV treatment?
8. Dana's story: What challenges and successes have you had with PV treatment?
Dana's story: What advice do you have for others on their journey with PV?
9. Dana's story: What advice do you have for others on their journey with PV?

How is polycythemia vera (PV) diagnosed? — Expert Video

Professor of Medicine, Dr. John Mascarenhas, provides an overview of how polycythemia vera (PV) is diagnosed. PV is often first suspected when a routine blood test shows elevated blood cell counts, though some people are referred for symptoms such as headaches, an enlarged spleen, or blood clots. Dr. Mascarenhas emphasizes the importance of a baseline bone marrow biopsy, which confirms the diagnosis, evaluates fibrosis, and allows for genetic testing through next-generation sequencing (NGS) from the source of the bone marrow. He also explains the variant allele fraction (VAF), which measures the proportion of cells carrying the JAK2 mutation and helps estimate disease burden over time.

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Other Modules:

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Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Myelofibrosis (MF)

Myelofibrosis (MF)

Understanding and Diagnosing Polycythemia Vera (PV) — Animation
Understanding and Diagnosing Polycythemia Vera (PV) — Animation
Managing and Treating Polycythemia Vera (PV) — Animation
Managing and Treating Polycythemia Vera (PV) — Animation
Understanding and Diagnosing Polycythemia Vera (PV) — Slide Show
Understanding and Diagnosing Polycythemia Vera (PV) — Slide Show
Managing and Treating Polycythemia Vera (PV) — Slide Show
Managing and Treating Polycythemia Vera (PV) — Slide Show
Expert Videos
What is polycythemia vera (PV)?
1. What is polycythemia vera (PV)?
Why and how did my polycythemia vera (PV) arise?
2. Why and how did my polycythemia vera (PV) arise?
How is polycythemia vera (PV) diagnosed?
3. How is polycythemia vera (PV) diagnosed?
What are the signs, symptoms, and expectations of living with PV?
4. What are the signs, symptoms, and expectations of living with PV?
What are the risks with polycythemia vera (PV)?
5. What are the risks with polycythemia vera (PV)?
How is polycythemia vera (PV) managed and treated?
6. How is polycythemia vera (PV) managed and treated?
Patient Videos
Dana's story: How did you find out you had polycythemia vera (PV)?
7. Dana's story: How did you find out you had polycythemia vera (PV)?
Dana's story: What challenges and successes have you had with PV treatment?
8. Dana's story: What challenges and successes have you had with PV treatment?
Dana's story: What advice do you have for others on their journey with PV?
9. Dana's story: What advice do you have for others on their journey with PV?

Other Modules:

Understanding MPNs

Understanding MPNs

Essential Thrombocythemia (ET)

Essential Thrombocythemia (ET)

Myelofibrosis (MF)

Myelofibrosis (MF)

 

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